Study helps unravel why pregnant women develop heart failure similar to older patients

Researchers at Penn Medicine have identified more genetic mutations that strongly predispose younger, otherwise healthy women to peripartum cardiomyopathy (PPCM), a rare condition characterized by weakness of the heart muscle that begins sometime during the final month of pregnancy through five months after delivery. PPCM can cause severe heart failure and often leads to lifelong […]

Continue Reading

Statistical model helps predict when high blood pressure, heart disease and diabetes will occur

One of the promises of new methods of personalized medicine is that individual risks for diseases can be assessed using large DNA datasets. But many diseases are highly multifactorial, meaning that genetic risk factors are spread throughout the DNA. Finding these elusive connections and constructing a reliable and trackable statistical model from them is the […]

Continue Reading

Gender-affirming treatment impacts cholesterol levels

Gender-affirming hormone treatments caused cholesterol levels to increase for transfeminine individuals and to decrease for transmasculine individuals, according to a study published in JAMA Pediatrics. Robert Garofalo, MD, MPH, the Potocsnak Family Professor in Adolescent & Young Adult Medicine, chief of Adolescent Medicine in the Department of Pediatrics and a professor of Preventive Medicine, was […]

Continue Reading